(2-chloro-6-methylpyridin-3-yl)boronic acid - Names and Identifiers
(2-chloro-6-methylpyridin-3-yl)boronic acid - Physico-chemical Properties
Molecular Formula | C6H7BClNO2
|
Molar Mass | 171.39 |
Density | 1.34 |
Boling Point | 338.7±52.0 °C(Predicted) |
Flash Point | 158.6°C |
Vapor Presure | 3.76E-05mmHg at 25°C |
pKa | 6.85±0.58(Predicted) |
Storage Condition | 2-8°C |
Refractive Index | 1.55 |
(2-chloro-6-methylpyridin-3-yl)boronic acid - Introduction
boronic acid is an organic boron compound with the chemical formula C6H7BClNO2. Its molecular structure contains a boron atom, a chlorine atom, a methyl group and a pyridine ring.
This compound has high chemical stability and is soluble in many organic solvents, such as dimethylformamide and dichloromethane. It is a white crystalline solid that is stable at room temperature.
boronic acid is mainly used as an important intermediate in organic synthesis. It can be used in the synthesis of various other compounds, such as drugs, pesticides, complexes, etc. In addition, it can also be used as a ligand in organometallic catalysts.
Preparation of (Ti) boronic acid is usually carried out by adding boric acid or dimethyl borate to a solution of 2-chloro-6-methylpyridine.
When operating, you need to pay attention to the safety of the compound. It may be irritating to the skin, eyes and respiratory tract, so direct contact should be avoided. Appropriate personal protective equipment, such as lab gloves, goggles and face shields, should be worn during use. During storage and transportation, contact with strong oxidants and strong acids should be avoided to prevent fire and explosion.
Last Update:2024-04-09 20:52:54